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Maresin 1 protects the liver against ischemia/reperfusion injury via the ALXR/Akt signaling pathway
Author / Creator:Tang, Da ; Fu, Guang ; Li, Wenbo ; Sun, Ping ; Loughran, Patricia A ; Deng, Meihong ; Scott, Melanie J ; Billiar, Timothy R
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2021-02, Vol.27 (1), p.18-18, Article 18
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Signaling of high mobility group box 1 (HMGB1) through toll-like receptor 4 in macrophages requires CD14
Author / Creator:Kim, Sodam ; Kim, Sun Young ; Pribis, John P ; Lotze, Michael ; Mollen, Kevin P ; Shapiro, Richard ; Loughran, Patricia ; Scott, Melanie J ; Billiar, Timothy R
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2013-01, Vol.19 (1), p.88-98
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Gasdermin D protects against noninfectious liver injury by regulating apoptosis and necroptosis
Author / Creator:Yang, Chenxuan ; Sun, Ping ; Deng, Meihong ; Loughran, Patricia ; Li, Wenbo ; Yi, Zhongjie ; Li, Shilai ; Zhang, Xianghong ; Fan, Jie ; Billiar, Timothy R. ; Scott, Melanie J
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2019-06, Vol.10 (7), p.481-10, Article 481
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Interferon Regulatory Factor-1 (IRF1) activates autophagy to promote liver ischemia/reperfusion injury by inhibiting β-catenin in mice
Author / Creator:Yan, Bing ; Luo, Jing ; Kaltenmeier, Christof ; Du, Qiang ; Stolz, Donna B ; Loughran, Patricia ; Yan, Yihe ; Cui, Xiao ; Geller, David A
Publisher:United States: Public Library of Science
Journal title:PloS one, 2020-11, Vol.15 (11), p.e0239119-e0239119
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Toll-like receptor 4 (TLR4) antagonist eritoran tetrasodium attenuates liver ischemia and reperfusion injury through inhibition of high-mobility group box protein B1 (HMGB1) signaling
Author / Creator:Mcdonald, Kerry-Ann ; Huang, Hai ; Tohme, Samer ; Loughran, Patricia ; Ferrero, Kimberly ; Billiar, Timothy ; Tsung, Allan
Publisher:United States: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2014, Vol.20 (1), p.639-648
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Interleukin‐33 contributes to ILC2 activation and early inflammation‐associated lung injury during abdominal sepsis
Author / Creator:Xu, Hui ; Xu, Jing ; Xu, Li ; Jin, Shuqing ; Turnquist, Heth R ; Hoffman, Rosemary ; Loughran, Patricia ; Billiar, Timothy R ; Deng, Meihong
Publisher:United States: Blackwell Science Ltd
Journal title:Immunology and cell biology, 2018-10, Vol.96 (9), p.935-947
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Mechanism of lactic acidemia-promoted pulmonary endothelial cells death in sepsis: role for CIRP-ZBP1-PANoptosis pathway
Author / Creator:Gong, Ting ; Wang, Qing-De ; Loughran, Patricia A ; Li, Yue-Hua ; Scott, Melanie J ; Billiar, Timothy R ; Liu, You-Tan ; Fan, Jie
Publisher:England: BioMed Central
Journal title:Military medical research, 2024-10, Vol.11 (1), p.71-24, Article 71
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Augmenting autophagy to treat acute kidney injury during endotoxemia in mice
Author / Creator:Howell, Gina M ; Gomez, Hernando ; Collage, Richard D ; Loughran, Patricia ; Zhang, Xianghong ; Escobar, Daniel A ; Billiar, Timothy R ; Zuckerbraun, Brian S ; Rosengart, Matthew R
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-07, Vol.8 (7), p.e69520
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Decoding the multiple functions of ZBP1 in the mechanism of sepsis-induced acute lung injury
Author / Creator:Gong, Ting ; Fu, Yu ; Wang, Qingde ; Loughran, Patricia A. ; Li, Yuehua ; Billiar, Timothy R. ; Wen, Zongmei ; Liu, Youtan ; Fan, Jie
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2024-10, Vol.7 (1), p.1361-18, Article 1361
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Caspase1/11 signaling affects muscle regeneration and recovery following ischemia, and can be modulated by chloroquine
Author / Creator:Sachdev, Ulka ; Ferrari, Ricardo ; Cui, Xiangdong ; Pius, Abish ; Sahu, Amrita ; Reynolds, Michael ; Liao, Hong ; Sun, Ping ; Shinde, Sunita ; Ambrosio, Fabrisia ; Shiva, Sruti ; Loughran, Patricia ; Scott, Melanie
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2020-07, Vol.26 (1), p.69-69, Article 69
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The platelet NLRP3 inflammasome is upregulated in a murine model of pancreatic cancer and promotes platelet aggregation and tumor growth
Author / Creator:Boone, Brian A. ; Murthy, Pranav ; Miller-Ocuin, Jennifer L. ; Liang, Xiaoyan ; Russell, Kira L. ; Loughran, Patricia ; Gawaz, Meinrad ; Lotze, Michael T. ; Zeh, Herbert J. ; Vogel, Sebastian
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Annals of hematology, 2019-07, Vol.98 (7), p.1603-1610
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Caspase-1 is hepatoprotective during trauma and hemorrhagic shock by reducing liver injury and inflammation
Author / Creator:Menzel, Christoph L ; Sun, Qian ; Loughran, Patricia A ; Pape, Hans-Christoph ; Billiar, Timothy R ; Scott, Melanie J
Publisher:England: ScholarOne
Journal title:Molecular medicine (Cambridge, Mass.), 2011-09, Vol.17 (9-10), p.1031-1038
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ZLN005, a PGC-1α Activator, Protects the Liver against Ischemia-Reperfusion Injury and the Progression of Hepatic Metastases
Author / Creator:Tohme, Celine ; Haykal, Tony ; Yang, Ruiqi ; Austin, Taylor J ; Loughran, Patricia ; Geller, David A ; Simmons, Richard L ; Tohme, Samer ; Yazdani, Hamza O
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2024-08, Vol.13 (17), p.1448
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Encouraging long‐term survival following autophagy inhibition using neoadjuvant hydroxychloroquine and gemcitabine for high‐risk patients with resectable pancreatic carcinoma
Author / Creator:AlMasri, Samer S. ; Zenati, Mazen S. ; Desilva, Annissa ; Nassour, Ibrahim ; Boone, Brian A. ; Singhi, Aatur D. ; Bartlett, David L. ; Liotta, Lance A. ; Espina, Virginia ; Loughran, Patricia ; Lotze, Michael T. ; Paniccia, Alessandro ; Zeh, Herbert J. ; Zureikat, Amer H. ; Bahary, Nathan
Publisher:United States: John Wiley & Sons, Inc
Journal title:Cancer medicine (Malden, MA), 2021-10, Vol.10 (20), p.7233-7241
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Inhaled Carbon Monoxide Protects against the Development of Shock and Mitochondrial Injury following Hemorrhage and Resuscitation
Author / Creator:Gomez, Hernando ; Kautza, Benjamin ; Escobar, Daniel ; Nassour, Ibrahim ; Luciano, Jason ; Botero, Ana Maria ; Gordon, Lisa ; Martinez, Silvia ; Holder, Andre ; Ogundele, Olufunmilayo ; Loughran, Patricia ; Rosengart, Matthew R ; Pinsky, Michael ; Shiva, Sruti ; Zuckerbraun, Brian S
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-09, Vol.10 (9), p.e0135032
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Inflammatory Caspase Activity Mediates HMGB1 Release and Differentiation in Myoblasts Affected by Peripheral Arterial Disease
Author / Creator:Ferrari, Ricardo ; Xie, Bowen ; Assaf, Edwyn ; Morder, Kristin ; Scott, Melanie ; Liao, Hong ; Calderon, Michael J ; Ross, Mark ; Loughran, Patricia ; Watkins, Simon C ; Pipinos, Iraklis ; Casale, George ; Tzeng, Edith ; McEnaney, Ryan ; Sachdev, Ulka
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2022-03, Vol.11 (7), p.1163
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Changes in FADD levels, distribution, and phosphorylation in TNFα-induced apoptosis in hepatocytes is caspase-3, caspase-8 and BID dependent
Author / Creator:Zhang, Xiaoying ; Vallabhaneni, Raghuveer ; Loughran, Patricia A ; Shapiro, Richard ; Yin, Xiao-Min ; Yuan, Youzhong ; Billiar, Timothy R
Publisher:Boston: Boston : Springer US
Journal title:Apoptosis (London), 2008-08, Vol.13 (8), p.983-992
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Gender-based reciprocal expression of transforming growth factor-β1 and the inducible nitric oxide synthase in a rat model of cyclophosphamide-induced cystitis
Author / Creator:Tyagi, Pradeep ; Tyagi, Vikas ; Yoshimura, Naoki ; Witteemer, Erich ; Barclay, Derek ; Loughran, Patricia A ; Zamora, Ruben ; Vodovotz, Yoram
Publisher:BioMed Central Ltd
Journal title:Journal of inflammation (London, England), 2009-08, Vol.6 (1), p.23-23, Article 23
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Deep vein thrombosis in mice is regulated by platelet HMGB1 through release of neutrophil-extracellular traps and DNA
Author / Creator:Dyer, Mitchell R. ; Chen, Qiwei ; Haldeman, Shannon ; Yazdani, Hamza ; Hoffman, Rosemary ; Loughran, Patricia ; Tsung, Allan ; Zuckerbraun, Brian S. ; Simmons, Richard L. ; Neal, Matthew D.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-02, Vol.8 (1), p.2068-7, Article 2068
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Platelet-derived HMGB1 is a critical mediator of thrombosis
Author / Creator:Vogel, Sebastian ; Bodenstein, Rebecca ; Chen, Qiwei ; Feil, Susanne ; Feil, Robert ; Rheinlaender, Johannes ; Schäffer, Tilman E ; Bohn, Erwin ; Frick, Julia-Stefanie ; Borst, Oliver ; Münzer, Patrick ; Walker, Britta ; Markel, Justin ; Csanyi, Gabor ; Pagano, Patrick J ; Loughran, Patricia ; Jessup, Morgan E ; Watkins, Simon C ; Bullock, Grant C ; Sperry, Jason L ; Zuckerbraun, Brian S ; Billiar, Timothy R ; Lotze, Michael T ; Gawaz, Meinrad ; Neal, Matthew D
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2015-12, Vol.125 (12), p.4638-4654
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Maresin 1 protects the liver against ischemia/reperfusion injury via the ALXR/Akt signaling pathway

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Signaling of high mobility group box 1 (HMGB1) through toll-like receptor 4 in macrophages requires CD14

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Gasdermin D protects against noninfectious liver injury by regulating apoptosis and necroptosis

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Interferon Regulatory Factor-1 (IRF1) activates autophagy to promote liver ischemia/reperfusion injury by inhibiting β-catenin in mice

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Toll-like receptor 4 (TLR4) antagonist eritoran tetrasodium attenuates liver ischemia and reperfusion injury through inhibition of high-mobility group box protein B1 (HMGB1) signaling

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Interleukin‐33 contributes to ILC2 activation and early inflammation‐associated lung injury during abdominal sepsis

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Mechanism of lactic acidemia-promoted pulmonary endothelial cells death in sepsis: role for CIRP-ZBP1-PANoptosis pathway

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Augmenting autophagy to treat acute kidney injury during endotoxemia in mice

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Decoding the multiple functions of ZBP1 in the mechanism of sepsis-induced acute lung injury

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Caspase1/11 signaling affects muscle regeneration and recovery following ischemia, and can be modulated by chloroquine

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The platelet NLRP3 inflammasome is upregulated in a murine model of pancreatic cancer and promotes platelet aggregation and tumor growth

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Caspase-1 is hepatoprotective during trauma and hemorrhagic shock by reducing liver injury and inflammation

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ZLN005, a PGC-1α Activator, Protects the Liver against Ischemia-Reperfusion Injury and the Progression of Hepatic Metastases

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Encouraging long‐term survival following autophagy inhibition using neoadjuvant hydroxychloroquine and gemcitabine for high‐risk patients with resectable pancreatic carcinoma

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Inhaled Carbon Monoxide Protects against the Development of Shock and Mitochondrial Injury following Hemorrhage and Resuscitation

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Inflammatory Caspase Activity Mediates HMGB1 Release and Differentiation in Myoblasts Affected by Peripheral Arterial Disease

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Changes in FADD levels, distribution, and phosphorylation in TNFα-induced apoptosis in hepatocytes is caspase-3, caspase-8 and BID dependent

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Gender-based reciprocal expression of transforming growth factor-β1 and the inducible nitric oxide synthase in a rat model of cyclophosphamide-induced cystitis

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Deep vein thrombosis in mice is regulated by platelet HMGB1 through release of neutrophil-extracellular traps and DNA

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Platelet-derived HMGB1 is a critical mediator of thrombosis

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