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Patients with IgG1-anti-red blood cell autoantibodies show aberrant Fc-glycosylation

Patients with IgG1-anti-red blood cell autoantibodies show aberrant Fc-glycosylation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9331eca3284a4261ade0540383c4b35b

Patients with IgG1-anti-red blood cell autoantibodies show aberrant Fc-glycosylation

About this item

Full title

Patients with IgG1-anti-red blood cell autoantibodies show aberrant Fc-glycosylation

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-08, Vol.7 (1), p.8187-9, Article 8187

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Autoimmune hemolytic anemia (AIHA) is a potentially severe disease in which red blood cells (RBC) are destroyed by IgG anti-RBC autoantibodies which can lead to hemolysis. We recently found IgG Fc-glycosylation towards platelet and RBC alloantigens to be skewed towards decreased fucosylation, increased galactosylation and sialylation. The lowered c...

Alternative Titles

Full title

Patients with IgG1-anti-red blood cell autoantibodies show aberrant Fc-glycosylation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9331eca3284a4261ade0540383c4b35b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9331eca3284a4261ade0540383c4b35b

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-08654-y

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