Patients with IgG1-anti-red blood cell autoantibodies show aberrant Fc-glycosylation
Patients with IgG1-anti-red blood cell autoantibodies show aberrant Fc-glycosylation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Autoimmune hemolytic anemia (AIHA) is a potentially severe disease in which red blood cells (RBC) are destroyed by IgG anti-RBC autoantibodies which can lead to hemolysis. We recently found IgG Fc-glycosylation towards platelet and RBC alloantigens to be skewed towards decreased fucosylation, increased galactosylation and sialylation. The lowered c...
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Patients with IgG1-anti-red blood cell autoantibodies show aberrant Fc-glycosylation
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TN_cdi_doaj_primary_oai_doaj_org_article_9331eca3284a4261ade0540383c4b35b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9331eca3284a4261ade0540383c4b35b
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-08654-y