Nucleotide excision repair deficiency is a targetable therapeutic vulnerability in clear cell renal...
Nucleotide excision repair deficiency is a targetable therapeutic vulnerability in clear cell renal cell carcinoma
About this item
Full title
Author / Creator
Prosz, Aurel , Duan, Haohui , Tisza, Viktoria , Sahgal, Pranshu , Topka, Sabine , Klus, Gregory T. , Börcsök, Judit , Sztupinszki, Zsofia , Hanlon, Timothy , Diossy, Miklos , Vizkeleti, Laura , Stormoen, Dag Rune , Csabai, Istvan , Pappot, Helle , Vijai, Joseph , Offit, Kenneth , Ried, Thomas , Sethi, Nilay , Mouw, Kent W. , Spisak, Sandor , Pathania, Shailja and Szallasi, Zoltan
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Due to a demonstrated lack of DNA repair deficiencies, clear cell renal cell carcinoma (ccRCC) has not benefitted from targeted synthetic lethality-based therapies. We investigated whether nucleotide excision repair (NER) deficiency is present in an identifiable subset of ccRCC cases that would render those tumors sensitive to therapy targeting thi...
Alternative Titles
Full title
Nucleotide excision repair deficiency is a targetable therapeutic vulnerability in clear cell renal cell carcinoma
Authors, Artists and Contributors
Author / Creator
Duan, Haohui
Tisza, Viktoria
Sahgal, Pranshu
Topka, Sabine
Klus, Gregory T.
Börcsök, Judit
Sztupinszki, Zsofia
Hanlon, Timothy
Diossy, Miklos
Vizkeleti, Laura
Stormoen, Dag Rune
Csabai, Istvan
Pappot, Helle
Vijai, Joseph
Offit, Kenneth
Ried, Thomas
Sethi, Nilay
Mouw, Kent W.
Spisak, Sandor
Pathania, Shailja
Szallasi, Zoltan
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_939969bbc4324201be410156a45cd9e5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_939969bbc4324201be410156a45cd9e5
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-47946-4
