Integrated molecular characterization reveals potential therapeutic strategies for pulmonary sarcoma...
Integrated molecular characterization reveals potential therapeutic strategies for pulmonary sarcomatoid carcinoma
About this item
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Author / Creator
Yang, Zhenlin , Xu, Jiachen , Li, Lin , Li, Renda , Wang, Yalong , Tian, Yanhua , Guo, Wei , Wang, Zhijie , Tan, Fengwei , Ying, Jianming , Jiao, Yuchen , Gao, Shugeng , Wang, Jie , Gao, Yibo and He, Jie
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Pulmonary sarcomatoid carcinoma (PSC) is a rare subtype of lung cancer with poor prognosis. Here, we perform multi-omics analysis of 56 PSC samples, 14 of which are microdissected to analyze intratumoral heterogeneity. We report the mutational landscape of PSC. The epithelial and sarcomatoid components share numerous genomic alterations, indicating...
Alternative Titles
Full title
Integrated molecular characterization reveals potential therapeutic strategies for pulmonary sarcomatoid carcinoma
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9450754d048f4b36a59fec1342fbe22f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9450754d048f4b36a59fec1342fbe22f
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-18702-3
