Fast-exchanging spirocyclic rhodamine probes for aptamer-based super-resolution RNA imaging
Fast-exchanging spirocyclic rhodamine probes for aptamer-based super-resolution RNA imaging
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Live-cell RNA imaging with high spatial and temporal resolution remains a major challenge. Here we report the development of RhoBAST:SpyRho, a fluorescent light-up aptamer (FLAP) system ideally suited for visualizing RNAs in live or fixed cells with various advanced fluorescence microscopy modalities. Overcoming problems associated with low cell pe...
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Full title
Fast-exchanging spirocyclic rhodamine probes for aptamer-based super-resolution RNA imaging
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TN_cdi_doaj_primary_oai_doaj_org_article_9497349644eb460a9fa92b4db02b0bfb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9497349644eb460a9fa92b4db02b0bfb
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-39611-1
