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U1 snRNP regulates cancer cell migration and invasion in vitro

U1 snRNP regulates cancer cell migration and invasion in vitro

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_94e6334d86c641beb8ea3c082c7fc160

U1 snRNP regulates cancer cell migration and invasion in vitro

About this item

Full title

U1 snRNP regulates cancer cell migration and invasion in vitro

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-01, Vol.11 (1), p.1-1, Article 1

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Stimulated cells and cancer cells have widespread shortening of mRNA 3’-untranslated regions (3’UTRs) and switches to shorter mRNA isoforms due to usage of more proximal polyadenylation signals (PASs) in introns and last exons. U1 snRNP (U1), vertebrates’ most abundant non-coding (spliceosomal) small nuclear RNA, silences proximal PASs and its inhi...

Alternative Titles

Full title

U1 snRNP regulates cancer cell migration and invasion in vitro

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_94e6334d86c641beb8ea3c082c7fc160

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_94e6334d86c641beb8ea3c082c7fc160

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-13993-7

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