Higher CSF sTREM2 and microglia activation are associated with slower rates of beta‐amyloid accumula...
Higher CSF sTREM2 and microglia activation are associated with slower rates of beta‐amyloid accumulation
About this item
Full title
Author / Creator
Alzheimer's Disease Neuroimaging Initiative (ADNI) , the Alzheimer's Disease Neuroimaging Initiative (ADNI) , Ewers, Michael , Biechele, Gloria , Suárez‐Calvet, Marc , Sacher, Christian , Blume, Tanja , Morenas‐Rodriguez, Estrella , Deming, Yuetiva , Piccio, Laura , Cruchaga, Carlos , Kleinberger, Gernot , Shaw, Leslie , Trojanowski, John Q , Herms, Jochen , Dichgans, Martin , Brendel, Matthias , Haass, Christian and Franzmeier, Nicolai
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Microglia activation is the brain's major immune response to amyloid plaques in Alzheimer's disease (AD). Both cerebrospinal fluid (CSF) levels of soluble TREM2 (sTREM2), a biomarker of microglia activation, and microglia PET are increased in AD; however, whether an increase in these biomarkers is associated with reduced amyloid‐beta (Aβ) accumulat...
Alternative Titles
Full title
Higher CSF sTREM2 and microglia activation are associated with slower rates of beta‐amyloid accumulation
Authors, Artists and Contributors
Author / Creator
the Alzheimer's Disease Neuroimaging Initiative (ADNI)
Ewers, Michael
Biechele, Gloria
Suárez‐Calvet, Marc
Sacher, Christian
Blume, Tanja
Morenas‐Rodriguez, Estrella
Deming, Yuetiva
Piccio, Laura
Cruchaga, Carlos
Kleinberger, Gernot
Shaw, Leslie
Trojanowski, John Q
Herms, Jochen
Dichgans, Martin
Brendel, Matthias
Haass, Christian
Franzmeier, Nicolai
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9500415c117547ba868021c5c4d1ca2c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9500415c117547ba868021c5c4d1ca2c
Other Identifiers
ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.202012308
