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Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Org...

Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Org...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9550ae6160b44a838337eb3885f4db0c

Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Organ Regeneration

About this item

Full title

Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Organ Regeneration

Publisher

Germany: John Wiley & Sons, Inc

Journal title

Advanced science, 2021-07, Vol.8 (14), p.2100626-n/a

Language

English

Formats

Publication information

Publisher

Germany: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Somatic cell reprogramming and tissue repair share relevant factors and molecular programs. Here, Dickkopf‐3 (DKK3) is identified as novel factor for organ regeneration using combined transcription‐factor‐induced reprogramming and RNA‐interference techniques. Loss of Dkk3 enhances the generation of induced pluripotent stem cells but does not affect...

Alternative Titles

Full title

Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Organ Regeneration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9550ae6160b44a838337eb3885f4db0c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9550ae6160b44a838337eb3885f4db0c

Other Identifiers

ISSN

2198-3844

E-ISSN

2198-3844

DOI

10.1002/advs.202100626

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