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104 results for Kleger,+Alexander

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ArticlesPeer ReviewedFull Text
DNA damage repair as a target in pancreatic cancer: state-of-the-art and future perspectives
Author / Creator:Perkhofer, Lukas ; Gout, Johann ; Roger, Elodie ; Kude de Almeida, Fernando ; Baptista Simões, Carolina ; Wiesmüller, Lisa ; Seufferlein, Thomas ; Kleger, Alexander
Publisher:England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title:Gut, 2021-03, Vol.70 (3), p.606-617
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IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro
Author / Creator:Prelli Bozzo, Caterina ; Nchioua, Rayhane ; Volcic, Meta ; Koepke, Lennart ; Krüger, Jana ; Schütz, Desiree ; Heller, Sandra ; Stürzel, Christina M. ; Kmiec, Dorota ; Conzelmann, Carina ; Müller, Janis ; Zech, Fabian ; Braun, Elisabeth ; Groß, Rüdiger ; Wettstein, Lukas ; Weil, Tatjana ; Weiß, Johanna ; Diofano, Federica ; Rodríguez Alfonso, Armando A. ; Wiese, Sebastian ; Sauter, Daniel ; Münch, Jan ; Goffinet, Christine ; Catanese, Alberto ; Schön, Michael ; Boeckers, Tobias M. ; Stenger, Steffen ; Sato, Kei ; Just, Steffen ; Kleger, Alexander ; Sparrer, Konstantin M. J. ; Kirchhoff, Frank
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-07, Vol.12 (1), p.4584-4584, Article 4584
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Spike residue 403 affects binding of coronavirus spikes to human ACE2
Author / Creator:Zech, Fabian ; Schniertshauer, Daniel ; Jung, Christoph ; Herrmann, Alexandra ; Cordsmeier, Arne ; Xie, Qinya ; Nchioua, Rayhane ; Prelli Bozzo, Caterina ; Volcic, Meta ; Koepke, Lennart ; Müller, Janis A. ; Krüger, Jana ; Heller, Sandra ; Stenger, Steffen ; Hoffmann, Markus ; Pöhlmann, Stefan ; Kleger, Alexander ; Jacob, Timo ; Conzelmann, Karl-Klaus ; Ensser, Armin ; Sparrer, Konstantin M. J. ; Kirchhoff, Frank
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-11, Vol.12 (1), p.6855-6855, Article 6855
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Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection
Author / Creator:Wettstein, Lukas ; Weil, Tatjana ; Conzelmann, Carina ; Müller, Janis A. ; Groß, Rüdiger ; Hirschenberger, Maximilian ; Seidel, Alina ; Klute, Susanne ; Zech, Fabian ; Prelli Bozzo, Caterina ; Preising, Nico ; Fois, Giorgio ; Lochbaum, Robin ; Knaff, Philip Maximilian ; Mailänder, Volker ; Ständker, Ludger ; Thal, Dietmar Rudolf ; Schumann, Christian ; Stenger, Steffen ; Kleger, Alexander ; Lochnit, Günter ; Mayer, Benjamin ; Ruiz-Blanco, Yasser B. ; Hoffmann, Markus ; Sparrer, Konstantin M. J. ; Pöhlmann, Stefan ; Sanchez-Garcia, Elsa ; Kirchhoff, Frank ; Frick, Manfred ; Münch, Jan
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-03, Vol.12 (1), p.1726-1726, Article 1726
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A pancreatic cancer organoid-in-matrix platform shows distinct sensitivities to T cell killing
Author / Creator:Lahusen, Anton ; Cai, Jierui ; Schirmbeck, Reinhold ; Wellstein, Anton ; Kleger, Alexander ; Seufferlein, Thomas ; Eiseler, Tim ; Lin, Yuan-Na
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-04, Vol.14 (1), p.9377-9377, Article 9377
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Synergistic targeting and resistance to PARP inhibition in DNA damage repair-deficient pancreatic cancer
Author / Creator:Gout, Johann ; Perkhofer, Lukas ; Morawe, Mareen ; Arnold, Frank ; Ihle, Michaela ; Biber, Stephanie ; Lange, Sebastian ; Roger, Elodie ; Kraus, Johann M ; Stifter, Katja ; Hahn, Stephan A ; Zamperone, Andrea ; Engleitner, Thomas ; Müller, Martin ; Walter, Karolin ; Rodriguez-Aznar, Eva ; Sainz Jr, Bruno ; Hermann, Patrick C ; Hessmann, Elisabeth ; Müller, Sebastian ; Azoitei, Ninel ; Lechel, André ; Liebau, Stefan ; Wagner, Martin ; Simeone, Diane M ; Kestler, Hans A ; Seufferlein, Thomas ; Wiesmüller, Lisa ; Rad, Roland ; Frappart, Pierre-Olivier ; Kleger, Alexander
Publisher:England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title:Gut, 2021-04, Vol.70 (4), p.743-760
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Implementing an electromagnetic tracking navigation system improves the precision of endoscopic transgastric necrosectomy in an ex vivo model
Author / Creator:Fichtl, Anna ; Sheikhani, Alaan ; Wagner, Martin ; Kleger, Alexander ; Müller, Martin ; Sturm, Niklas ; Walter, Benjamin ; Franz, Alfred Michael
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-05, Vol.14 (1), p.10055-10055, Article 10055
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PPDPF is not a key regulator of human pancreas development
Author / Creator:Breunig, Markus ; Hohwieler, Meike ; Haderspeck, Jasmin ; von Zweydorf, Felix ; Hauff, Natalie ; Pasquini, Lino-Pascal ; Wiegreffe, Christoph ; Zimmer, Eleni ; Mulaw, Medhanie A. ; Julier, Cécile ; Simon, Eric ; Gloeckner, Christian Johannes ; Liebau, Stefan ; Kleger, Alexander
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2025-04, Vol.21 (4), p.e1011657
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ArticlesPeer ReviewedFull Text
Pandemic punch: SARS-CoV-2 hits pancreas
Author / Creator:Azoitei, Ninel ; Heller, Sandra ; Kleger, Alexander
Publisher:London: Nature Publishing Group UK
Journal title:Signal transduction and targeted therapy, 2024-04, Vol.9 (1), p.100-100, Article 100
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Single-cell-resolved differentiation of human induced pluripotent stem cells into pancreatic duct-like organoids on a microwell chip
Author / Creator:Wiedenmann, Sandra ; Breunig, Markus ; Merkle, Jessica ; von Toerne, Christine ; Georgiev, Tihomir ; Moussus, Michel ; Schulte, Lucas ; Seufferlein, Thomas ; Sterr, Michael ; Lickert, Heiko ; Weissinger, Stephanie Ellen ; Möller, Peter ; Hauck, Stefanie M. ; Hohwieler, Meike ; Kleger, Alexander ; Meier, Matthias
Publisher:London: Nature Publishing Group UK
Journal title:Nature biomedical engineering, 2021-08, Vol.5 (8), p.897-913
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ArticlesPeer ReviewedFull Text
Loss of ATM accelerates pancreatic cancer formation and epithelial–mesenchymal transition
Author / Creator:Russell, Ronan ; Perkhofer, Lukas ; Liebau, Stefan ; Lin, Qiong ; Lechel, André ; Feld, Fenja M ; Hessmann, Elisabeth ; Gaedcke, Jochen ; Güthle, Melanie ; Zenke, Martin ; Hartmann, Daniel ; von Figura, Guido ; Weissinger, Stephanie E ; Rudolph, Karl-Lenhard ; Möller, Peter ; Lennerz, Jochen K ; Seufferlein, Thomas ; Wagner, Martin ; Kleger, Alexander
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-07, Vol.6 (1), p.7677-7677, Article 7677
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ArticlesPeer ReviewedFull Text
Human Serum Albumin Is an Essential Component of the Host Defense Mechanism Against Clostridium difficile Intoxication
Author / Creator:di Masi, Alessandra ; Leboffe, Loris ; Polticelli, Fabio ; Tonon, Federica ; Zennaro, Cristina ; Caterino, Marianna ; Stano, Pasquale ; Fischer, Stephan ; Hägele, Marlen ; Müller, Martin ; Kleger, Alexander ; Papatheodorou, Panagiotis ; Nocca, Giuseppina ; Arcovito, Alessandro ; Gori, Andrea ; Ruoppolo, Margherita ; Barth, Holger ; Petrosillo, Nicola ; Ascenzi, Paolo ; Di Bella, Stefano
Publisher:United States
Journal title:The Journal of infectious diseases, 2018-09, Vol.218 (9), p.1424-1435
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Treatment monitoring in metastatic colorectal cancer patients by quantification and KRAS genotyping of circulating cell-free DNA
Author / Creator:Berger, Andreas W. ; Schwerdel, Daniel ; Welz, Hanna ; Marienfeld, Ralf ; Schmidt, Stefan A. ; Kleger, Alexander ; Ettrich, Thomas J. ; Seufferlein, Thomas
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-03, Vol.12 (3), p.e0174308-e0174308
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An Immunological Glance on Pancreatic Ductal Adenocarcinoma
Author / Creator:Melzer, Michael Karl ; Arnold, Frank ; Stifter, Katja ; Zengerling, Friedemann ; Azoitei, Ninel ; Seufferlein, Thomas ; Bolenz, Christian ; Kleger, Alexander
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-05, Vol.21 (9), p.3345
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Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation
Author / Creator:Heller, Sandra ; Li, Zhijian ; Lin, Qiong ; Geusz, Ryan ; Breunig, Markus ; Hohwieler, Meike ; Zhang, Xi ; Nair, Gopika G. ; Seufferlein, Thomas ; Hebrok, Matthias ; Sander, Maike ; Julier, Cécile ; Kleger, Alexander ; Costa, Ivan G.
Publisher:London: Nature Publishing Group UK
Journal title:Communications biology, 2021-11, Vol.4 (1), p.1298-1298, Article 1298
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Impairment of α-tubulin and F-actin interactions of GJB3 induces aneuploidy in urothelial cells and promotes bladder cancer cell invasion
Author / Creator:Liu, Junnan ; Wang, Xue ; Jiang, Wencheng ; Azoitei, Anca ; Eiseler, Tim ; Eckstein, Markus ; Hartmann, Arndt ; Stilgenbauer, Stephan ; Elati, Mohamed ; Hohwieler, Meike ; Kleger, Alexander ; John, Axel ; Wezel, Felix ; Zengerling, Friedemann ; Bolenz, Christian ; Günes, Cagatay
Publisher:England: BioMed Central
Journal title:Cellular & molecular biology letters, 2024-07, Vol.29 (1), p.94-29, Article 94
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Self-Expandable Metal Stents for Persisting Esophageal Variceal Bleeding after Band Ligation or Injection-Therapy: A Retrospective Study
Author / Creator:Müller, Martin ; Seufferlein, Thomas ; Perkhofer, Lukas ; Wagner, Martin ; Kleger, Alexander
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-06, Vol.10 (6), p.e0126525-e0126525
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A Three-Dimensional Engineered Cardiac In Vitro Model: Controlled Alignment of Cardiomyocytes in 3D Microphysiological Systems
Author / Creator:Navaee, Fatemeh ; Khornian, Niloofar ; Longet, David ; Heub, Sarah ; Boder-Pasche, Stephanie ; Weder, Gilles ; Kleger, Alexander ; Renaud, Philippe ; Braschler, Thomas
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2023-02, Vol.12 (4), p.576
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Generation of Functional Vascular Endothelial Cells and Pericytes from Keratinocyte Derived Human Induced Pluripotent Stem Cells
Author / Creator:Pars, Selin ; Achberger, Kevin ; Kleger, Alexander ; Liebau, Stefan ; Pashkovskaia, Natalia
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2021-01, Vol.10 (1), p.74
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Hsp70 facilitates trans-membrane transport of bacterial ADP-ribosylating toxins into the cytosol of mammalian cells
Author / Creator:Ernst, Katharina ; Schmid, Johannes ; Beck, Matthias ; Hägele, Marlen ; Hohwieler, Meike ; Hauff, Patricia ; Ückert, Anna Katharina ; Anastasia, Anna ; Fauler, Michael ; Jank, Thomas ; Aktories, Klaus ; Popoff, Michel R. ; Schiene-Fischer, Cordelia ; Kleger, Alexander ; Müller, Martin ; Frick, Manfred ; Barth, Holger
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-06, Vol.7 (1), p.2724-16, Article 2724
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DNA damage repair as a target in pancreatic cancer: state-of-the-art and future perspectives

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IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro

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Spike residue 403 affects binding of coronavirus spikes to human ACE2

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Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection

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A pancreatic cancer organoid-in-matrix platform shows distinct sensitivities to T cell killing

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Synergistic targeting and resistance to PARP inhibition in DNA damage repair-deficient pancreatic cancer

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Implementing an electromagnetic tracking navigation system improves the precision of endoscopic transgastric necrosectomy in an ex vivo model

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PPDPF is not a key regulator of human pancreas development

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Pandemic punch: SARS-CoV-2 hits pancreas

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Single-cell-resolved differentiation of human induced pluripotent stem cells into pancreatic duct-like organoids on a microwell chip

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Loss of ATM accelerates pancreatic cancer formation and epithelial–mesenchymal transition

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Human Serum Albumin Is an Essential Component of the Host Defense Mechanism Against Clostridium difficile Intoxication

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Treatment monitoring in metastatic colorectal cancer patients by quantification and KRAS genotyping of circulating cell-free DNA

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An Immunological Glance on Pancreatic Ductal Adenocarcinoma

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Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation

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Impairment of α-tubulin and F-actin interactions of GJB3 induces aneuploidy in urothelial cells and promotes bladder cancer cell invasion

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Self-Expandable Metal Stents for Persisting Esophageal Variceal Bleeding after Band Ligation or Injection-Therapy: A Retrospective Study

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A Three-Dimensional Engineered Cardiac In Vitro Model: Controlled Alignment of Cardiomyocytes in 3D Microphysiological Systems

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Generation of Functional Vascular Endothelial Cells and Pericytes from Keratinocyte Derived Human Induced Pluripotent Stem Cells

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Hsp70 facilitates trans-membrane transport of bacterial ADP-ribosylating toxins into the cytosol of mammalian cells

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