A transcriptomic map of EGFR-induced epithelial-to-mesenchymal transition identifies prognostic and...
A transcriptomic map of EGFR-induced epithelial-to-mesenchymal transition identifies prognostic and therapeutic targets for head and neck cancer
About this item
Full title
Author / Creator
Schinke, Henrik , Shi, Enxian , Lin, Zhongyang , Quadt, Tanja , Kranz, Gisela , Zhou, Jiefu , Wang, Hongxia , Hess, Julia , Heuer, Steffen , Belka, Claus , Zitzelsberger, Horst , Schumacher, Udo , Genduso, Sandra , Riecken, Kristoffer , Gao, Yujing , Wu, Zhengquan , Reichel, Christoph A. , Walz, Christoph , Canis, Martin , Unger, Kristian , Baumeister, Philipp , Pan, Min and Gires, Olivier
Publisher
London: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
London: BioMed Central Ltd
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Scope and Contents
Contents
Background Epidermal growth factor receptor (EGFR) is both a driver oncogene and a therapeutic target in advanced head and neck squamous cell carcinoma (HNSCC). However, response to EGFR treatment is inconsistent and lacks markers for treatment prediction. This study investigated EGFR-induced epithelial-to-mesenchymal transition (EMT) as a central...
Alternative Titles
Full title
A transcriptomic map of EGFR-induced epithelial-to-mesenchymal transition identifies prognostic and therapeutic targets for head and neck cancer
Authors, Artists and Contributors
Author / Creator
Shi, Enxian
Lin, Zhongyang
Quadt, Tanja
Kranz, Gisela
Zhou, Jiefu
Wang, Hongxia
Hess, Julia
Heuer, Steffen
Belka, Claus
Zitzelsberger, Horst
Schumacher, Udo
Genduso, Sandra
Riecken, Kristoffer
Gao, Yujing
Wu, Zhengquan
Reichel, Christoph A.
Walz, Christoph
Canis, Martin
Unger, Kristian
Baumeister, Philipp
Pan, Min
Gires, Olivier
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_95531d59b79a463e83a7c5658acca70f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_95531d59b79a463e83a7c5658acca70f
Other Identifiers
ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-022-01646-1
