Notch-mediated conversion of activated T cells into stem cell memory-like T cells for adoptive immun...
Notch-mediated conversion of activated T cells into stem cell memory-like T cells for adoptive immunotherapy
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Adoptive T-cell immunotherapy is a promising approach to cancer therapy. Stem cell memory T (T
SCM
) cells have been proposed as a class of long-lived and highly proliferative memory T cells. CD8
+
T
SCM
cells can be generated
in vitro
from naive CD8
+
T cells via Wnt signalling; however, methods do not yet exist for i...
Alternative Titles
Full title
Notch-mediated conversion of activated T cells into stem cell memory-like T cells for adoptive immunotherapy
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_956f24e4dd8a4d5881a8d99fc61d6ef7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_956f24e4dd8a4d5881a8d99fc61d6ef7
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms15338
