EV71 5'UTR interacts with 3D protein affecting replication through the AKT-mTOR pathway
EV71 5'UTR interacts with 3D protein affecting replication through the AKT-mTOR pathway
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Author / Creator
Xu, Xiaoying , Ma, Shao , Liu, Ziwei , Yuan, Haowen , Wang, Yao , Chen, Mengting , Du, Mengyu , Kan, Haopeng , Wang, Zequn , Chong, Xiaowen and Wen, Hongling
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
EV71 is one of the important pathogens of Hand-foot-and-mouth disease (HFMD), which causes serious neurological symptoms. Several studies have speculated that there will be interaction between 5'UTR and 3D protein. However, whether 5'UTR interacts with the 3D protein in regulating virus replication has not been clarified.
Four 5'UTR mutation sit...
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Full title
EV71 5'UTR interacts with 3D protein affecting replication through the AKT-mTOR pathway
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9574eca6bc2e4e8ca780abba813b9bc7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9574eca6bc2e4e8ca780abba813b9bc7
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ISSN
1743-422X
E-ISSN
1743-422X
DOI
10.1186/s12985-024-02385-z