Essential role for InSyn1 in dystroglycan complex integrity and cognitive behaviors in mice
Essential role for InSyn1 in dystroglycan complex integrity and cognitive behaviors in mice
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England: eLife Science Publications, Ltd
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English
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England: eLife Science Publications, Ltd
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Human mutations in the dystroglycan complex (DGC) result in not only muscular dystrophy but also cognitive impairments. However, the molecular architecture critical for the synaptic organization of the DGC in neurons remains elusive. Here, we report Inhibitory Synaptic protein 1 (InSyn1) is a critical component of the DGC whose loss alters the comp...
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Full title
Essential role for InSyn1 in dystroglycan complex integrity and cognitive behaviors in mice
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TN_cdi_doaj_primary_oai_doaj_org_article_962ab3557d38497e91e4e12fb85d02bf
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_962ab3557d38497e91e4e12fb85d02bf
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.50712
