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Differential impact of self and environmental antigens on the ontogeny and maintenance of CD4+ T cel...

Differential impact of self and environmental antigens on the ontogeny and maintenance of CD4+ T cel...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_96567a4133f546699da8b9140eb311df

Differential impact of self and environmental antigens on the ontogeny and maintenance of CD4+ T cell memory

About this item

Full title

Differential impact of self and environmental antigens on the ontogeny and maintenance of CD4+ T cell memory

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2019-11, Vol.8

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

Laboratory mice develop populations of circulating memory CD4+ T cells in the absence of overt infection. We have previously shown that these populations are replenished from naive precursors at high levels throughout life (Gossel et al., 2017). However, the nature, relative importance and timing of the forces generating these cells remain unclear....

Alternative Titles

Full title

Differential impact of self and environmental antigens on the ontogeny and maintenance of CD4+ T cell memory

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_96567a4133f546699da8b9140eb311df

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_96567a4133f546699da8b9140eb311df

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.48901

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