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ArticlesPeer ReviewedFull Text
Flip the coin: IL-7 and IL-7R in health and disease
Author / Creator:Barata, João ; Durum, Scott K. ; Seddon, Benedict
Publisher:New York: Springer Nature
Journal title:Nature immunology, 2019-12, Vol.20 (12), p.1584-1593
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Don Mason (1934–2021)
Author / Creator:Seddon, Benedict ; Powrie, Fiona ; Barclay, Neil
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2021-04, Vol.22 (4), p.395-395
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ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation
Author / Creator:Pearson, Claire ; Thornton, Emily E ; McKenzie, Brent ; Schaupp, Anna-Lena ; Huskens, Nicky ; Griseri, Thibault ; West, Nathaniel ; Tung, Sim ; Seddon, Benedict P ; Uhlig, Holm H ; Powrie, Fiona
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2016-01, Vol.5, p.e10066-e10066
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Memory CD4 T cell subsets are kinetically heterogeneous and replenished from naive T cells at high levels
Author / Creator:Gossel, Graeme ; Hogan, Thea ; Cownden, Daniel ; Seddon, Benedict ; Yates, Andrew J
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2017-03, Vol.6
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Age is not just a number: Naive T cells increase their ability to persist in the circulation over time
Author / Creator:Rane, Sanket ; Hogan, Thea ; Seddon, Benedict ; Yates, Andrew J.
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2018-04, Vol.16 (4), p.e2003949-e2003949
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The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development
Author / Creator:Gascoyne, Duncan M ; Long, Elaine ; Veiga-Fernandes, Henrique ; de Boer, Jasper ; Williams, Owen ; Seddon, Benedict ; Coles, Mark ; Kioussis, Dimitris ; Brady, Hugh J M
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2009-10, Vol.10 (10), p.1118-1124
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Asymmetric thymocyte death underlies the CD4:CD8 T-cell ratio in the adaptive immune system
Author / Creator:Sinclair, Charles ; Bains, Iren ; Yates, Andrew J. ; Seddon, Benedict
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (31), p.E2905-E2914
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Towards a unified model of naive T cell dynamics across the lifespan
Author / Creator:Rane, Sanket ; Hogan, Thea ; Lee, Edward ; Seddon, Benedict ; Yates, Andrew J
Publisher:England: eLife Sciences Publications, Ltd
Journal title:eLife, 2022-06, Vol.11
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Temporal fate mapping reveals age-linked heterogeneity in naive T lymphocytes in mice
Author / Creator:Hogan, Thea ; Gossel, Graeme ; Yates, Andrew J. ; Seddon, Benedict
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (50), p.E6917-E6926
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The dynamics and longevity of circulating CD4+ memory T cells depend on cell age and not the chronological age of the host
Author / Creator:Bullock, M. Elise ; Hogan, Thea ; Williams, Cayman ; Morris, Sinead ; Nowicka, Maria ; Sharjeel, Minahil ; van Dorp, Christiaan ; Yates, Andrew J. ; Seddon, Benedict
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2024-08, Vol.22 (8), p.e3002380
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Differential impact of self and environmental antigens on the ontogeny and maintenance of CD4+ T cell memory
Author / Creator:Hogan, Thea ; Nowicka, Maria ; Cownden, Daniel ; Pearson, Claire F ; Yates, Andrew J ; Seddon, Benedict
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2019-11, Vol.8
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NF-κB signaling mediates homeostatic maturation of new T cells
Author / Creator:Silva, Ana ; Cornish, Georgina ; Ley, Steven C. ; Seddon, Benedict
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (9), p.3212-3212
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Interleukin-7 Influences FOXP3+CD4+ Regulatory T Cells Peripheral Homeostasis
Author / Creator:Simonetta, Federico ; Gestermann, Nicolas ; Martinet, Kim Zita ; Boniotto, Michele ; Tissières, Pierre ; Seddon, Benedict ; Bourgeois, Christine
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-05, Vol.7 (5), p.e36596-e36596
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Spatial Heterogeneity and Peptide Availability Determine CTL Killing Efficiency In Vivo
Author / Creator:Hogan, Thea ; Kadolsky, Ulrich ; Tung, Sim ; Seddon, Benedict ; Yates, Andrew
Publisher:United States: Public Library of Science
Journal title:PLoS computational biology, 2014-09, Vol.10 (9), p.e1003805-e1003805
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Tissue Specific Deletion of Inhibitor of Kappa B Kinase 2 with OX40-Cre Reveals the Unanticipated Expression from the OX40 Locus in Skin Epidermis
Author / Creator:Cornish, Georgina H. ; Tung, Sim L. ; Marshall, Daniel ; Ley, Steve ; Seddon, Benedict P.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-02, Vol.7 (2), p.e32193
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Homeostatic Proliferation and IL-7R Alpha Expression Do Not Correlate with Enhanced T Cell Proliferation and Protection in Chronic Mouse Malaria
Author / Creator:Stephens, Robin ; Seddon, Benedict ; Langhorne, Jean
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-10, Vol.6 (10), p.e26686-e26686
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Models of Self-Peptide Sampling by Developing T Cells Identify Candidate Mechanisms of Thymic Selection
Author / Creator:Bains, Iren ; van Santen, Hisse M. ; Seddon, Benedict ; Yates, Andrew J.
Publisher:United States: Public Library of Science
Journal title:PLoS computational biology, 2013-07, Vol.9 (7), p.e1003102
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Long-term survival but impaired homeostatic proliferation of naive T cells in the absence of p56(lck)
Author / Creator:Benedict Seddon Giuseppe Legname ; Tomlinson, Peter ; Rose Zamoyska
Publisher:Washington: The American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2000-10, Vol.290 (5489), p.127-131
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Evidence of STAT5‐dependent and ‐independent routes to CD8 memory formation and a preferential role for IL‐7 over IL‐15 in STAT5 activation
Author / Creator:Kemp, Roslyn A ; Pearson, Claire F ; Cornish, Georgina H ; Seddon, Benedict P
Publisher:United States: Nature Publishing Group
Journal title:Immunology and cell biology, 2010-02, Vol.88 (2), p.213-219
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Thymic IL-7 signaling goes beyond survival
Author / Creator:Seddon, Benedict
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2015-04, Vol.16 (4), p.337-338
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Showing 1 to 20 of 45 results

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Flip the coin: IL-7 and IL-7R in health and disease

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Don Mason (1934–2021)

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ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation

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Memory CD4 T cell subsets are kinetically heterogeneous and replenished from naive T cells at high levels

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Age is not just a number: Naive T cells increase their ability to persist in the circulation over time

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The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development

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Asymmetric thymocyte death underlies the CD4:CD8 T-cell ratio in the adaptive immune system

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Towards a unified model of naive T cell dynamics across the lifespan

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Temporal fate mapping reveals age-linked heterogeneity in naive T lymphocytes in mice

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The dynamics and longevity of circulating CD4+ memory T cells depend on cell age and not the chronological age of the host

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Differential impact of self and environmental antigens on the ontogeny and maintenance of CD4+ T cell memory

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NF-κB signaling mediates homeostatic maturation of new T cells

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Interleukin-7 Influences FOXP3+CD4+ Regulatory T Cells Peripheral Homeostasis

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Spatial Heterogeneity and Peptide Availability Determine CTL Killing Efficiency In Vivo

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Tissue Specific Deletion of Inhibitor of Kappa B Kinase 2 with OX40-Cre Reveals the Unanticipated Expression from the OX40 Locus in Skin Epidermis

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Homeostatic Proliferation and IL-7R Alpha Expression Do Not Correlate with Enhanced T Cell Proliferation and Protection in Chronic Mouse Malaria

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Models of Self-Peptide Sampling by Developing T Cells Identify Candidate Mechanisms of Thymic Selection

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Long-term survival but impaired homeostatic proliferation of naive T cells in the absence of p56(lck)

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Evidence of STAT5‐dependent and ‐independent routes to CD8 memory formation and a preferential role for IL‐7 over IL‐15 in STAT5 activation

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Thymic IL-7 signaling goes beyond survival

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