Moderate lifelong overexpression of tuberous sclerosis complex 1 (TSC1) improves health and survival...
Moderate lifelong overexpression of tuberous sclerosis complex 1 (TSC1) improves health and survival in mice
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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The tuberous sclerosis complex 1/2 (TSC1/2) is an endogenous regulator of the mechanistic target of rapamycin (mTOR). While mTOR has been shown to play an important role in health and aging, the role of TSC1/2 in aging has not been fully investigated. In the current study, a constitutive TSC1 transgenic (
Tsc1
tg
) mouse model was generate...
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Full title
Moderate lifelong overexpression of tuberous sclerosis complex 1 (TSC1) improves health and survival in mice
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TN_cdi_doaj_primary_oai_doaj_org_article_96ca9655468d43eba1428c6922390f67
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_96ca9655468d43eba1428c6922390f67
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-00970-7
