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Population pharmacokinetic and exposure–response analyses of intravenous and subcutaneous rituximab...

Population pharmacokinetic and exposure–response analyses of intravenous and subcutaneous rituximab...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_96de8a1a1020405cb52160c9fa76dd90

Population pharmacokinetic and exposure–response analyses of intravenous and subcutaneous rituximab in patients with chronic lymphocytic leukemia

About this item

Full title

Population pharmacokinetic and exposure–response analyses of intravenous and subcutaneous rituximab in patients with chronic lymphocytic leukemia

Publisher

United States: John Wiley & Sons, Inc

Journal title

CPT: pharmacometrics and systems pharmacology, 2021-08, Vol.10 (8), p.914-927

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

A subcutaneous formulation of the anti‐CD20 antibody rituximab has been developed. Fixed‐dose subcutaneous rituximab delivers noninferior serum trough concentrations (Ctrough), ensuring similar target saturation and comparable efficacy/safety, to intravenous rituximab, but with simplified and shortened preparation and administration. We aimed to ch...

Alternative Titles

Full title

Population pharmacokinetic and exposure–response analyses of intravenous and subcutaneous rituximab in patients with chronic lymphocytic leukemia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_96de8a1a1020405cb52160c9fa76dd90

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_96de8a1a1020405cb52160c9fa76dd90

Other Identifiers

ISSN

2163-8306

E-ISSN

2163-8306

DOI

10.1002/psp4.12665

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