A cross-reactive human IgA monoclonal antibody blocks SARS-CoV-2 spike-ACE2 interaction
A cross-reactive human IgA monoclonal antibody blocks SARS-CoV-2 spike-ACE2 interaction
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Author / Creator
Ejemel, Monir , Li, Qi , Hou, Shurong , Schiller, Zachary A. , Tree, Julia A. , Wallace, Aaron , Amcheslavsky, Alla , Kurt Yilmaz, Nese , Buttigieg, Karen R. , Elmore, Michael J. , Godwin, Kerry , Coombes, Naomi , Toomey, Jacqueline R. , Schneider, Ryan , Ramchetty, Anudeep S. , Close, Brianna J. , Chen, Da-Yuan , Conway, Hasahn L. , Saeed, Mohsan , Ganesa, Chandrashekar , Carroll, Miles W. , Cavacini, Lisa A. , Klempner, Mark S. , Schiffer, Celia A. and Wang, Yang
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
COVID-19 caused by SARS-CoV-2 has become a global pandemic requiring the development of interventions for the prevention or treatment to curtail mortality and morbidity. No vaccine to boost mucosal immunity, or as a therapeutic, has yet been developed to SARS-CoV-2. In this study, we discover and characterize a cross-reactive human IgA monoclonal a...
Alternative Titles
Full title
A cross-reactive human IgA monoclonal antibody blocks SARS-CoV-2 spike-ACE2 interaction
Authors, Artists and Contributors
Author / Creator
Li, Qi
Hou, Shurong
Schiller, Zachary A.
Tree, Julia A.
Wallace, Aaron
Amcheslavsky, Alla
Kurt Yilmaz, Nese
Buttigieg, Karen R.
Elmore, Michael J.
Godwin, Kerry
Coombes, Naomi
Toomey, Jacqueline R.
Schneider, Ryan
Ramchetty, Anudeep S.
Close, Brianna J.
Chen, Da-Yuan
Conway, Hasahn L.
Saeed, Mohsan
Ganesa, Chandrashekar
Carroll, Miles W.
Cavacini, Lisa A.
Klempner, Mark S.
Schiffer, Celia A.
Wang, Yang
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_97644dca295e44a19fa5676282d05155
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_97644dca295e44a19fa5676282d05155
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-18058-8