Tau exacerbates excitotoxic brain damage in an animal model of stroke
Tau exacerbates excitotoxic brain damage in an animal model of stroke
About this item
Full title
Author / Creator
Bi, Mian , Gladbach, Amadeus , van Eersel, Janet , Ittner, Arne , Przybyla, Magdalena , van Hummel, Annika , Chua, Sook Wern , van der Hoven, Julia , Lee, Wei S. , Müller, Julius , Parmar, Jasneet , Jonquieres, Georg von , Stefen, Holly , Guccione, Ernesto , Fath, Thomas , Housley, Gary D. , Klugmann, Matthias , Ke, Yazi D. and Ittner, Lars M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Neuronal excitotoxicity induced by aberrant excitation of glutamatergic receptors contributes to brain damage in stroke. Here we show that tau-deficient (tau
−/−
) mice are profoundly protected from excitotoxic brain damage and neurological deficits following experimental stroke, using a middle cerebral artery occlusion with reperfusion model...
Alternative Titles
Full title
Tau exacerbates excitotoxic brain damage in an animal model of stroke
Authors, Artists and Contributors
Author / Creator
Gladbach, Amadeus
van Eersel, Janet
Ittner, Arne
Przybyla, Magdalena
van Hummel, Annika
Chua, Sook Wern
van der Hoven, Julia
Lee, Wei S.
Müller, Julius
Parmar, Jasneet
Jonquieres, Georg von
Stefen, Holly
Guccione, Ernesto
Fath, Thomas
Housley, Gary D.
Klugmann, Matthias
Ke, Yazi D.
Ittner, Lars M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_97fd15d6e4f1429dae0533cf6a3311e1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_97fd15d6e4f1429dae0533cf6a3311e1
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-00618-0
