Regulation of gene expression by the APP family in the adult cerebral cortex
Regulation of gene expression by the APP family in the adult cerebral cortex
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Amyloid precursor protein (APP) is associated with both familial and sporadic forms of Alzheimer’s disease. APP has two homologs, amyloid precursor-like protein 1 and 2 (APLP1 and APLP2), and they have functional redundancy. APP intracellular c-terminal domain (AICD), produced by sequential α- or β- and γ-secretase cleavages, is thought to control...
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Full title
Regulation of gene expression by the APP family in the adult cerebral cortex
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TN_cdi_doaj_primary_oai_doaj_org_article_9826e28eaec544188f9f607d5edd5035
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9826e28eaec544188f9f607d5edd5035
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-04027-8
