Log in to save to my catalogue

Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects b...

Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects b...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9832f21d253e45ed88430bd1eb8d43d4

Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects brain connectivity

About this item

Full title

Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects brain connectivity

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2017-10, Vol.8 (1), p.1214-13, Article 1214

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

It is not known exactly where amyloid-β (Aβ) fibrils begin to accumulate in individuals with Alzheimer’s disease (AD). Recently, we showed that abnormal levels of Aβ42 in cerebrospinal fluid (CSF) can be detected before abnormal amyloid can be detected using PET in individuals with preclinical AD. Using these approaches, here we identify the earlie...

Alternative Titles

Full title

Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects brain connectivity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9832f21d253e45ed88430bd1eb8d43d4

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9832f21d253e45ed88430bd1eb8d43d4

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-017-01150-x