Evaluation of human gene variant detection in amplicon pools by the GS-FLX parallel Pyrosequencer
Evaluation of human gene variant detection in amplicon pools by the GS-FLX parallel Pyrosequencer
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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A new priority in genome research is large-scale resequencing of genes to understand the molecular basis of hereditary disease and cancer. We assessed the ability of massively parallel pyrosequencing to identify sequence variants in pools. From a large collection of human PCR samples we selected 343 PCR products belonging to 16 disease genes and in...
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Full title
Evaluation of human gene variant detection in amplicon pools by the GS-FLX parallel Pyrosequencer
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TN_cdi_doaj_primary_oai_doaj_org_article_9854313ddd9d4a6dacaace05065c883c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9854313ddd9d4a6dacaace05065c883c
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ISSN
1471-2164
E-ISSN
1471-2164
DOI
10.1186/1471-2164-9-464
