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Drosophila macrophages switch to aerobic glycolysis to mount effective antibacterial defense

Drosophila macrophages switch to aerobic glycolysis to mount effective antibacterial defense

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_988c82f9ff7246d7af99d3165741a2d1

Drosophila macrophages switch to aerobic glycolysis to mount effective antibacterial defense

About this item

Full title

Drosophila macrophages switch to aerobic glycolysis to mount effective antibacterial defense

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2019-10, Vol.8

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

Macrophage-mediated phagocytosis and cytokine production represent the front lines of resistance to bacterial invaders. A key feature of this pro-inflammatory response in mammals is the complex remodeling of cellular metabolism towards aerobic glycolysis. Although the function of bactericidal macrophages is highly conserved, the metabolic remodelin...

Alternative Titles

Full title

Drosophila macrophages switch to aerobic glycolysis to mount effective antibacterial defense

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_988c82f9ff7246d7af99d3165741a2d1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_988c82f9ff7246d7af99d3165741a2d1

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.50414

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