Inflammation promotes synucleinopathy propagation
Inflammation promotes synucleinopathy propagation
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The clinical progression of neurodegenerative diseases correlates with the spread of proteinopathy in the brain. The current understanding of the mechanism of proteinopathy spread is far from complete. Here, we propose that inflammation is fundamental to proteinopathy spread. A sequence variant of α-synuclein (V40G) was much less capable of fibril...
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Full title
Inflammation promotes synucleinopathy propagation
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TN_cdi_doaj_primary_oai_doaj_org_article_99a88b201f584b40bda54e3a13392c78
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_99a88b201f584b40bda54e3a13392c78
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ISSN
2092-6413,1226-3613
E-ISSN
2092-6413
DOI
10.1038/s12276-022-00895-w
