Intratumor heterogeneity: the hidden barrier to immunotherapy against MSI tumors from the perspectiv...
Intratumor heterogeneity: the hidden barrier to immunotherapy against MSI tumors from the perspective of IFN-γ signaling and tumor-infiltrating lymphocytes
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Author / Creator
Wu, Wantao , Liu, Yihan , Zeng, Shan , Han, Ying and Shen, Hong
Publisher
London: BioMed Central
Journal title
Language
English
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Publication information
Publisher
London: BioMed Central
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Scope and Contents
Contents
In this era of precision medicine, with the help of biomarkers, immunotherapy has significantly improved prognosis of many patients with malignant tumor. Deficient mismatch repair (dMMR)/microsatellite instability (MSI) status is used as a biomarker in clinical practice to predict favorable response to immunotherapy and prognosis. MSI is an importa...
Alternative Titles
Full title
Intratumor heterogeneity: the hidden barrier to immunotherapy against MSI tumors from the perspective of IFN-γ signaling and tumor-infiltrating lymphocytes
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Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_99ed10f60944450a9dd6f6c81ed1f339
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_99ed10f60944450a9dd6f6c81ed1f339
Other Identifiers
ISSN
1756-8722
E-ISSN
1756-8722
DOI
10.1186/s13045-021-01166-3
