METTL3-mediated m6A modification of LINC00839 maintains glioma stem cells and radiation resistance b...
METTL3-mediated m6A modification of LINC00839 maintains glioma stem cells and radiation resistance by activating Wnt/β-catenin signaling
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Author / Creator
Yin, Jianxing , Ding, Fangshu , Cheng, Zhangchun , Ge, Xin , Li, Yanhui , Zeng, Ailiang , Zhang, Junxia , Yan, Wei , Shi, Zhumei , Qian, Xu , You, Yongping , Ding, Zhiliang , Ji, Jing and Wang, Xiefeng
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
Long noncoding RNAs (lncRNAs) are involved in glioma initiation and progression. Glioma stem cells (GSCs) are essential for tumor initiation, maintenance, and therapeutic resistance. However, the biological functions and underlying mechanisms of lncRNAs in GSCs remain poorly understood. Here, we identified that LINC00839 was overexpressed in GSCs....
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Full title
METTL3-mediated m6A modification of LINC00839 maintains glioma stem cells and radiation resistance by activating Wnt/β-catenin signaling
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_99f11da15a63462d9198ce0ec0f0d457
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_99f11da15a63462d9198ce0ec0f0d457
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-023-05933-7
