Ultrastructural analysis of adult mouse neocortex comparing aldehyde perfusion with cryo fixation
Ultrastructural analysis of adult mouse neocortex comparing aldehyde perfusion with cryo fixation
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England: eLife Sciences Publications, Ltd
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English
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England: eLife Sciences Publications, Ltd
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Analysis of brain ultrastructure using electron microscopy typically relies on chemical fixation. However, this is known to cause significant tissue distortion including a reduction in the extracellular space. Cryo fixation is thought to give a truer representation of biological structures, and here we use rapid, high-pressure freezing on adult mou...
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Ultrastructural analysis of adult mouse neocortex comparing aldehyde perfusion with cryo fixation
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TN_cdi_doaj_primary_oai_doaj_org_article_9a316c9731be4461a5d080328ffa53a6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9a316c9731be4461a5d080328ffa53a6
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.05793
