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Genetic deletion of Abcc6 disturbs cholesterol homeostasis in mice

Genetic deletion of Abcc6 disturbs cholesterol homeostasis in mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9a7807a95b5a4947b9f5a712694318ad

Genetic deletion of Abcc6 disturbs cholesterol homeostasis in mice

About this item

Full title

Genetic deletion of Abcc6 disturbs cholesterol homeostasis in mice

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2021-01, Vol.11 (1), p.2137-13, Article 2137

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Genetic studies link adenosine triphosphate-binding cassette transporter C6 (
ABCC6
) mutations to pseudoxanthoma elasticum (PXE).
ABCC6 s
equence variations are correlated with altered HDL cholesterol levels and an elevated risk of coronary artery diseases. However, the role of ABCC6 in cholesterol homeostasis is not widely known. Here...

Alternative Titles

Full title

Genetic deletion of Abcc6 disturbs cholesterol homeostasis in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9a7807a95b5a4947b9f5a712694318ad

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9a7807a95b5a4947b9f5a712694318ad

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-021-81573-1

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