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Cytotoxicity of portoamides in human cancer cells and analysis of the molecular mechanisms of action

Cytotoxicity of portoamides in human cancer cells and analysis of the molecular mechanisms of action

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9aed217840e147d4a048a3aeb5d52b37

Cytotoxicity of portoamides in human cancer cells and analysis of the molecular mechanisms of action

About this item

Full title

Cytotoxicity of portoamides in human cancer cells and analysis of the molecular mechanisms of action

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-12, Vol.12 (12), p.e0188817

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Portoamides are cyclic peptides produced and released by the cyanobacterial strain Phormidium sp. presumably to interfere with other organisms in their ecosystems ("allelopathy"). Portoamides were previously demonstrated to have an antiproliferative effect on human lung carcinoma cells, but the underlying mechanism of this activity has not been des...

Alternative Titles

Full title

Cytotoxicity of portoamides in human cancer cells and analysis of the molecular mechanisms of action

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9aed217840e147d4a048a3aeb5d52b37

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9aed217840e147d4a048a3aeb5d52b37

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0188817