The Current State-of-the Art of LRRK2-Based Biomarker Assay Development in Parkinson’s Disease
The Current State-of-the Art of LRRK2-Based Biomarker Assay Development in Parkinson’s Disease
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Lausanne: Frontiers Research Foundation
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Language
English
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Lausanne: Frontiers Research Foundation
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Contents
Evidence is mounting that LRRK2 activity, particularly its kinase activity, is elevated in multiple forms of Parkinson’s disease, both idiopathic as well as familial forms linked to mutations in the LRRK2 gene. However, sensitive quantitative markers of LRRK2 activation in clinical samples remain at the early stages of development. There are severa...
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Full title
The Current State-of-the Art of LRRK2-Based Biomarker Assay Development in Parkinson’s Disease
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TN_cdi_doaj_primary_oai_doaj_org_article_9b99a1e11ad44ba693fc6e89a5f08950
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9b99a1e11ad44ba693fc6e89a5f08950
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ISSN
1662-453X,1662-4548
E-ISSN
1662-453X
DOI
10.3389/fnins.2020.00865
