A genome-wide cross-trait analysis identifies genomic correlation, pleiotropic loci, and causal rela...
A genome-wide cross-trait analysis identifies genomic correlation, pleiotropic loci, and causal relationship between sex hormone-binding globulin and rheumatoid arthritis
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London: BioMed Central Ltd
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English
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London: BioMed Central Ltd
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Background Our study aims to investigate an intrinsic link underlying sex hormone-binding globulin (SHBG) and rheumatoid arthritis (RA), which remains inconclusive in observational settings. Methods Summary statistics were collected from the largest GWAS(s) on SHBG adjusted for BMI (SHBG.sub.adjBMI; N.sub.overall = 368,929; N.sub.men = 180,094; N.s...
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A genome-wide cross-trait analysis identifies genomic correlation, pleiotropic loci, and causal relationship between sex hormone-binding globulin and rheumatoid arthritis
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TN_cdi_doaj_primary_oai_doaj_org_article_9c29135ce7b04fa8b04e9e7a8f59547e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9c29135ce7b04fa8b04e9e7a8f59547e
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ISSN
1479-7364,1473-9542
E-ISSN
1479-7364
DOI
10.1186/s40246-023-00528-x
