FTO-associated osteoclastogenesis promotes alveolar bone resorption in apical periodontitis male rat...
FTO-associated osteoclastogenesis promotes alveolar bone resorption in apical periodontitis male rat via the HK1/USP14/RANK pathway
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Author / Creator
Qian, Yajie , Wu, Jing , Yang, Weidong , Lyu, Ruining , You, Qiao , Li, Jingjing , He, Qin , Zhuang, Yuan , Wang, Wenmei , Wang, Yong , Zhu, Yanan , Wu, Zhiwei and Chen, Deyan
Publisher
London: Nature Publishing Group UK
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Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
Alveolar bone resorption (ABR) is a key pathological manifestation in the development of apical periodontitis (AP) and contributes to the AP-associated tooth loss among AP patients in the clinic. However, the underlying mechanism of ABR development is largely unknown. Here we show, the total levels of N6-methyladenosine (m
6
A) were reduced i...
Alternative Titles
Full title
FTO-associated osteoclastogenesis promotes alveolar bone resorption in apical periodontitis male rat via the HK1/USP14/RANK pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_9cefc2df618a454d80e0ba355851e9c1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9cefc2df618a454d80e0ba355851e9c1
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-56615-1
