Epigenetic drift of H3K27me3 in aging links glycolysis to healthy longevity in Drosophila
Epigenetic drift of H3K27me3 in aging links glycolysis to healthy longevity in Drosophila
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Author / Creator
Ma, Zaijun , Wang, Hui , Cai, Yuping , Wang, Han , Niu, Kongyan , Wu, Xiaofen , Ma, Huanhuan , Yang, Yun , Tong, Wenhua , Liu, Feng , Liu, Zhandong , Zhang, Yaoyang , Liu, Rui , Zhu, Zheng-Jiang and Liu, Nan
Publisher
England: eLife Sciences Publications Ltd
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Language
English
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Publisher
England: eLife Sciences Publications Ltd
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Contents
Epigenetic alteration has been implicated in aging. However, the mechanism by which epigenetic change impacts aging remains to be understood. H3K27me3, a highly conserved histone modification signifying transcriptional repression, is marked and maintained by Polycomb Repressive Complexes (PRCs). Here, we explore the mechanism by which age-modulated...
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Full title
Epigenetic drift of H3K27me3 in aging links glycolysis to healthy longevity in Drosophila
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TN_cdi_doaj_primary_oai_doaj_org_article_9cf7759066d24f918441bcbfdd73a2ff
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9cf7759066d24f918441bcbfdd73a2ff
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.35368
