Eighty-eight variants highlight the role of T cell regulation and airway remodeling in asthma pathog...
Eighty-eight variants highlight the role of T cell regulation and airway remodeling in asthma pathogenesis
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Author / Creator
Olafsdottir, Thorunn A. , Theodors, Fannar , Bjarnadottir, Kristbjorg , Bjornsdottir, Unnur Steina , Agustsdottir, Arna B. , Stefansson, Olafur A. , Ivarsdottir, Erna V. , Sigurdsson, Jon K. , Benonisdottir, Stefania , Eyjolfsson, Gudmundur I. , Gislason, David , Gislason, Thorarinn , Guðmundsdóttir, Steinunn , Gylfason, Arnaldur , Halldorsson, Bjarni V. , Halldorsson, Gisli H. , Juliusdottir, Thorhildur , Kristinsdottir, Anna M. , Ludviksdottir, Dora , Ludviksson, Bjorn R. , Masson, Gisli , Norland, Kristjan , Onundarson, Pall T. , Olafsson, Isleifur , Sigurdardottir, Olof , Stefansdottir, Lilja , Sveinbjornsson, Gardar , Tragante, Vinicius , Gudbjartsson, Daniel F. , Thorleifsson, Gudmar , Sulem, Patrick , Thorsteinsdottir, Unnur , Norddahl, Gudmundur L. , Jonsdottir, Ingileif and Stefansson, Kari
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Asthma is one of the most common chronic diseases affecting both children and adults. We report a genome-wide association meta-analysis of 69,189 cases and 702,199 controls from Iceland and UK biobank. We find 88 asthma risk variants at 56 loci, 19 previously unreported, and evaluate their effect on other asthma and allergic phenotypes. Of special...
Alternative Titles
Full title
Eighty-eight variants highlight the role of T cell regulation and airway remodeling in asthma pathogenesis
Authors, Artists and Contributors
Author / Creator
Theodors, Fannar
Bjarnadottir, Kristbjorg
Bjornsdottir, Unnur Steina
Agustsdottir, Arna B.
Stefansson, Olafur A.
Ivarsdottir, Erna V.
Sigurdsson, Jon K.
Benonisdottir, Stefania
Eyjolfsson, Gudmundur I.
Gislason, David
Gislason, Thorarinn
Guðmundsdóttir, Steinunn
Gylfason, Arnaldur
Halldorsson, Bjarni V.
Halldorsson, Gisli H.
Juliusdottir, Thorhildur
Kristinsdottir, Anna M.
Ludviksdottir, Dora
Ludviksson, Bjorn R.
Masson, Gisli
Norland, Kristjan
Onundarson, Pall T.
Olafsson, Isleifur
Sigurdardottir, Olof
Stefansdottir, Lilja
Sveinbjornsson, Gardar
Tragante, Vinicius
Gudbjartsson, Daniel F.
Thorleifsson, Gudmar
Sulem, Patrick
Thorsteinsdottir, Unnur
Norddahl, Gudmundur L.
Jonsdottir, Ingileif
Stefansson, Kari
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9d4c023806ed4deaa904e9b46d6dc5a9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9d4c023806ed4deaa904e9b46d6dc5a9
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-14144-8
