Human sensorimotor organoids derived from healthy and amyotrophic lateral sclerosis stem cells form...
Human sensorimotor organoids derived from healthy and amyotrophic lateral sclerosis stem cells form neuromuscular junctions
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Human induced pluripotent stem cells (iPSC) hold promise for modeling diseases in individual human genetic backgrounds and thus for developing precision medicine. Here, we generate sensorimotor organoids containing physiologically functional neuromuscular junctions (NMJs) and apply the model to different subgroups of amyotrophic lateral sclerosis (...
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Full title
Human sensorimotor organoids derived from healthy and amyotrophic lateral sclerosis stem cells form neuromuscular junctions
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TN_cdi_doaj_primary_oai_doaj_org_article_9db38ffd5c8547aa9bc606ed08d490ee
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9db38ffd5c8547aa9bc606ed08d490ee
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-24776-4
