Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated T...
Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Th17 and regulatory T (T
reg
) cells are integral in maintaining immune homeostasis and Th17–T
reg
imbalance is associated with inflammatory immunosuppression in cancer. Here we show that Th17 cells are a source of tumour-induced Foxp3
+
cells. In addition to natural (n)T
reg
and induced (i)T
reg
cells that develop fro...
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Full title
Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells
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TN_cdi_doaj_primary_oai_doaj_org_article_9e8d4eb2095e4915964c459f3f8ece80
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9e8d4eb2095e4915964c459f3f8ece80
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms14649