An Influenza A virus can evolve to use human ANP32E through altering polymerase dimerization
An Influenza A virus can evolve to use human ANP32E through altering polymerase dimerization
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Human ANP32A and ANP32B are essential but redundant host factors for influenza virus genome replication. While most influenza viruses cannot replicate in edited human cells lacking both ANP32A and ANP32B, some strains exhibit limited growth. Here, we experimentally evolve such an influenza A virus in these edited cells and unexpectedly, after 2 pas...
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Full title
An Influenza A virus can evolve to use human ANP32E through altering polymerase dimerization
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TN_cdi_doaj_primary_oai_doaj_org_article_9ea86ca4471f48e0947e131249f06d09
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9ea86ca4471f48e0947e131249f06d09
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-41308-4
