Mechanism of integrin activation by talin and its cooperation with kindlin
Mechanism of integrin activation by talin and its cooperation with kindlin
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Talin-induced integrin binding to extracellular matrix ligands (integrin activation) is the key step to trigger many fundamental cellular processes including cell adhesion, cell migration, and spreading. Talin is widely known to use its N-terminal head domain (talin-H) to bind and activate integrin, but how talin-H operates in the context of full-l...
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Full title
Mechanism of integrin activation by talin and its cooperation with kindlin
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TN_cdi_doaj_primary_oai_doaj_org_article_9ecb7d26bd11431887d1892b5ac0e1a8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9ecb7d26bd11431887d1892b5ac0e1a8
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-30117-w
