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Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pa...

Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pa...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9ecb955c84c24e09bbe549b3fd5de20b

Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer’s disease

About this item

Full title

Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer’s disease

Publisher

London: BioMed Central Ltd

Journal title

Acta neuropathologica communications, 2021-05, Vol.9 (1), p.1-93, Article 93

Language

English

Formats

Publication information

Publisher

London: BioMed Central Ltd

More information

Scope and Contents

Contents

Cerebral amyloid angiopathy (CAA) contributes to accelerated cognitive decline in Alzheimer's disease (AD) dementia and is a common finding at autopsy. The APOE[epsilon]4 allele and male sex have previously been reported to associate with increased CAA in AD. To inform biomarker and therapeutic target discovery, we aimed to identify additional gene...

Alternative Titles

Full title

Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer’s disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_9ecb955c84c24e09bbe549b3fd5de20b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9ecb955c84c24e09bbe549b3fd5de20b

Other Identifiers

ISSN

2051-5960

E-ISSN

2051-5960

DOI

10.1186/s40478-021-01199-2

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