Gefitinib and fostamatinib target EGFR and SYK to attenuate silicosis: a multi-omics study with drug...
Gefitinib and fostamatinib target EGFR and SYK to attenuate silicosis: a multi-omics study with drug exploration
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Author / Creator
Wang, Mingyao , Zhang, Zhe , Liu, Jiangfeng , Song, Meiyue , Zhang, Tiantian , Chen, Yiling , Hu, Huiyuan , Yang, Peiran , Li, Bolun , Song, Xiaomin , Pang, Junling , Xing, Yanjiang , Cao, Zhujie , Guo, Wenjun , Yang, Hao , Wang, Jing , Yang, Juntao and Wang, Chen
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Silicosis is the most prevalent and fatal occupational disease with no effective therapeutics, and currently used drugs cannot reverse the disease progress. Worse still, there are still challenges to be addressed to fully decipher the intricated pathogenesis. Thus, specifying the essential mechanisms and targets in silicosis progression then explor...
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Full title
Gefitinib and fostamatinib target EGFR and SYK to attenuate silicosis: a multi-omics study with drug exploration
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TN_cdi_doaj_primary_oai_doaj_org_article_9efc923f429f46c5aac80c35ecd10210
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9efc923f429f46c5aac80c35ecd10210
Other Identifiers
ISSN
2059-3635,2095-9907
E-ISSN
2059-3635
DOI
10.1038/s41392-022-00959-3
