Kindlin-2 in Sertoli cells is essential for testis development and male fertility in mice
Kindlin-2 in Sertoli cells is essential for testis development and male fertility in mice
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Author / Creator
Chi, Xiaochun , Luo, Weiwei , Song, Jiagui , Li, Bing , Su, Tiantian , Yu, Miao , Wang, Tianzhuo , Wang, Zhenbin , Liu, Cheng , Li, Zhen , He, Huiying , Zhan, Jun and Zhang, Hongquan
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Kindlin-2 is known to play important roles in the development of mesoderm-derived tissues including myocardium, smooth muscle, cartilage and blood vessels. However, nothing is known for the role of Kindlin-2 in mesoderm-derived reproductive organs. Here, we report that loss of Kindlin-2 in Sertoli cells caused severe testis hypoplasia, abnormal ger...
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Full title
Kindlin-2 in Sertoli cells is essential for testis development and male fertility in mice
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_9fd4fd42b903497dbc9a26be47970ed7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_9fd4fd42b903497dbc9a26be47970ed7
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-021-03885-4
