The tyrosine kinase KDR is essential for the survival of HTLV-1-infected T cells by stabilizing the...
The tyrosine kinase KDR is essential for the survival of HTLV-1-infected T cells by stabilizing the Tax oncoprotein
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Human T-cell leukemia virus type 1 (HTLV-1) infection is linked to the development of adult T-cell leukemia/lymphoma (ATLL) and the neuroinflammatory disease, HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The HTLV-1 Tax oncoprotein regulates viral gene expression and persistently activates NF-κB to maintain the viability of H...
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The tyrosine kinase KDR is essential for the survival of HTLV-1-infected T cells by stabilizing the Tax oncoprotein
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TN_cdi_doaj_primary_oai_doaj_org_article_a04449588b6a4f07960705a393a0b93e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a04449588b6a4f07960705a393a0b93e
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-49737-5
