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High-yield production of human Dicer by transfection of human HEK293-EBNA1 cells grown in suspension

High-yield production of human Dicer by transfection of human HEK293-EBNA1 cells grown in suspension

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a05d2271830643e2a4a1d9e1303d4e19

High-yield production of human Dicer by transfection of human HEK293-EBNA1 cells grown in suspension

About this item

Full title

High-yield production of human Dicer by transfection of human HEK293-EBNA1 cells grown in suspension

Publisher

England: BioMed Central Ltd

Journal title

BMC biotechnology, 2018-12, Vol.18 (1), p.76-76, Article 76

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Dicer is a 219-kDa protein that plays key roles in gene regulation, particularly as the ribonuclease III enzyme responsible for cleaving precursor miRNA substrates. Its enzymatic activity is highly regulated by protein factors, and this regulation can impact on the levels of miRNAs and modulate the behavior of a cell. To better understand the under...

Alternative Titles

Full title

High-yield production of human Dicer by transfection of human HEK293-EBNA1 cells grown in suspension

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a05d2271830643e2a4a1d9e1303d4e19

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a05d2271830643e2a4a1d9e1303d4e19

Other Identifiers

ISSN

1472-6750

E-ISSN

1472-6750

DOI

10.1186/s12896-018-0485-3

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