Statistical power and utility of meta-analysis methods for cross-phenotype genome-wide association s...
Statistical power and utility of meta-analysis methods for cross-phenotype genome-wide association studies
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Advances in recent genome wide association studies (GWAS) suggest that pleiotropic effects on human complex traits are widespread. A number of classic and recent meta-analysis methods have been used to identify genetic loci with pleiotropic effects, but the overall performance of these methods is not well understood. In this work, we use extensive...
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Statistical power and utility of meta-analysis methods for cross-phenotype genome-wide association studies
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TN_cdi_doaj_primary_oai_doaj_org_article_a0c4bdf5cad24252831df2400111f482
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a0c4bdf5cad24252831df2400111f482
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0193256