Oxidative stress mediates thalidomide-induced pain by targeting peripheral TRPA1 and central TRPV4
Oxidative stress mediates thalidomide-induced pain by targeting peripheral TRPA1 and central TRPV4
About this item
Full title
Author / Creator
De Logu, Francesco , Trevisan, Gabriela , Marone, Ilaria Maddalena , Coppi, Elisabetta , Padilha Dalenogare, Diéssica , Titiz, Mustafa , Marini, Matilde , Landini, Lorenzo , Souza Monteiro de Araujo, Daniel , Li Puma, Simone , Materazzi, Serena , De Siena, Gaetano , Geppetti, Pierangelo and Nassini, Romina
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
The mechanism underlying the pain symptoms associated with chemotherapeutic-induced peripheral neuropathy (CIPN) is poorly understood. Transient receptor potential ankyrin 1 (TRPA1), TRP vanilloid 4 (TRPV4), TRPV1, and oxidative stress have been implicated in several rodent models of CIPN-evoked allodynia. Thalidomide causes a painful CIPN in patie...
Alternative Titles
Full title
Oxidative stress mediates thalidomide-induced pain by targeting peripheral TRPA1 and central TRPV4
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a0d8d5c84ccf4ce5a3c61f688210f475
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a0d8d5c84ccf4ce5a3c61f688210f475
Other Identifiers
ISSN
1741-7007
E-ISSN
1741-7007
DOI
10.1186/s12915-020-00935-9
