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Autophagy inhibition elicits emergence from metastatic dormancy by inducing and stabilizing Pfkfb3 e...

Autophagy inhibition elicits emergence from metastatic dormancy by inducing and stabilizing Pfkfb3 e...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a138f0bd72854b59891da7dffc77c399

Autophagy inhibition elicits emergence from metastatic dormancy by inducing and stabilizing Pfkfb3 expression

About this item

Full title

Autophagy inhibition elicits emergence from metastatic dormancy by inducing and stabilizing Pfkfb3 expression

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-08, Vol.10 (1), p.3668-15, Article 3668

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Breast cancer stem cells (BCSCs) are unique in their ability to undergo unlimited self-renewal, an essential process in breast cancer recurrence following metastatic dormancy. Emergent metastatic lesions were subjected to microarray analysis, which identified 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (Pfkfb3) as a differentially express...

Alternative Titles

Full title

Autophagy inhibition elicits emergence from metastatic dormancy by inducing and stabilizing Pfkfb3 expression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a138f0bd72854b59891da7dffc77c399

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a138f0bd72854b59891da7dffc77c399

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-11640-9

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