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Deficiency of leucine-rich repeat kinase 2 aggravates thioacetamide-induced acute liver failure and...

Deficiency of leucine-rich repeat kinase 2 aggravates thioacetamide-induced acute liver failure and...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a14c983f31a0407d82156f8839601484

Deficiency of leucine-rich repeat kinase 2 aggravates thioacetamide-induced acute liver failure and hepatic encephalopathy in mice

About this item

Full title

Deficiency of leucine-rich repeat kinase 2 aggravates thioacetamide-induced acute liver failure and hepatic encephalopathy in mice

Publisher

England: BioMed Central Ltd

Journal title

Journal of neuroinflammation, 2024-05, Vol.21 (1), p.123-19, Article 123

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Hepatic encephalopathy (HE) is closely associated with inflammatory responses. However, as a crucial regulator of the immune and inflammatory responses, the role of leucine-rich repeat kinase 2 (LRRK2) in the pathogenesis of HE remains unraveled. Herein, we investigated this issue in thioacetamide (TAA)-induced HE following acute liver failure (ALF...

Alternative Titles

Full title

Deficiency of leucine-rich repeat kinase 2 aggravates thioacetamide-induced acute liver failure and hepatic encephalopathy in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a14c983f31a0407d82156f8839601484

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a14c983f31a0407d82156f8839601484

Other Identifiers

ISSN

1742-2094

E-ISSN

1742-2094

DOI

10.1186/s12974-024-03125-4

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