Pharmacological inhibition of α-synuclein aggregation within liquid condensates
Pharmacological inhibition of α-synuclein aggregation within liquid condensates
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Aggregated forms of α-synuclein constitute the major component of Lewy bodies, the proteinaceous aggregates characteristic of Parkinson’s disease. Emerging evidence suggests that α-synuclein aggregation may occur within liquid condensates formed through phase separation. This mechanism of aggregation creates new challenges and opportunities for dru...
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Pharmacological inhibition of α-synuclein aggregation within liquid condensates
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TN_cdi_doaj_primary_oai_doaj_org_article_a17360268c2c42ac8264f7fd9ce9115e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a17360268c2c42ac8264f7fd9ce9115e
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-47585-x
