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JNK and NADPH Oxidase Involved in Fluoride-Induced Oxidative Stress in BV-2 Microglia Cells

JNK and NADPH Oxidase Involved in Fluoride-Induced Oxidative Stress in BV-2 Microglia Cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a27583719fca4f77bdb266de63d5dd82

JNK and NADPH Oxidase Involved in Fluoride-Induced Oxidative Stress in BV-2 Microglia Cells

About this item

Full title

JNK and NADPH Oxidase Involved in Fluoride-Induced Oxidative Stress in BV-2 Microglia Cells

Publisher

Cairo, Egypt: Hindawi Limiteds

Journal title

Mediators of Inflammation, 2013-01, Vol.2013 (2013), p.188-197

Language

English

Formats

Publication information

Publisher

Cairo, Egypt: Hindawi Limiteds

More information

Scope and Contents

Contents

Excessive fluoride may cause central nervous system (CNS) dysfunction, and oxidative stress is a recognized mode of action of fluoride toxicity. In CNS, activated microglial cells can release more reactive oxygen species (ROS), and NADPH oxidase (NOX) is the major enzyme for the production of extracellular superoxide in microglia. ROS have been cha...

Alternative Titles

Full title

JNK and NADPH Oxidase Involved in Fluoride-Induced Oxidative Stress in BV-2 Microglia Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a27583719fca4f77bdb266de63d5dd82

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a27583719fca4f77bdb266de63d5dd82

Other Identifiers

ISSN

0962-9351

E-ISSN

1466-1861

DOI

10.1155/2013/895975

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