Design and Synthesis of Non-Covalent Imidazo[1,2- a ]quinoxaline-Based Inhibitors of EGFR and Their...
Design and Synthesis of Non-Covalent Imidazo[1,2- a ]quinoxaline-Based Inhibitors of EGFR and Their Anti-Cancer Assessment
About this item
Full title
Author / Creator
Publisher
Switzerland: MDPI AG
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: MDPI AG
Subjects
More information
Scope and Contents
Contents
A series of 30 non-covalent imidazo[1,2-
]quinoxaline-based inhibitors of epidermal growth factor receptor (EGFR) were designed and synthesized. EGFR inhibitory assessment (against wild type) data of compounds revealed
,
,
,
and
as potent EGFR
inhibitors with IC
values of 211.22, 222.21, 193.18, 223.32 and 221.53 nM, respect...
Alternative Titles
Full title
Design and Synthesis of Non-Covalent Imidazo[1,2- a ]quinoxaline-Based Inhibitors of EGFR and Their Anti-Cancer Assessment
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a2c5a397a2c640f19086505035070114
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a2c5a397a2c640f19086505035070114
Other Identifiers
ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules26051490
